Laboratorium Kimia Farmasi-Medisinal dan Bioanalisis

Laboratory of Pharmaceutical-Medicinal Chemistry and Bioanalysis

Laboratorium Kimia Farmasi-Medisinal dan Bioanalisis

Ketua dan Anggota Laboratorium Kimia Farmasi-Medisinal dan Bioanalisis

  • Dr. Hayun, M.Si., Apt. (Ketua)
  • Dr. Arry Yanuar, M.Si., Apt.
  • Prof. Dr. Harmita, Apt.
  • Dr. Herman Suryadi, M.Si., Apt.
  • Prof. Dr. Yahdiana Harahap, M.Si., Apt.
  • Euis Maras Purwati, M.Sc., Apt.
  • Baitha Palanggatan Maggadani, M.Farm., Apt.
  • Rezi Riadhi Syahdi, M.Farm.
  • Catur Jatmika, M.Si., Apt.
  • Arif Arrahman, M.Farm., Apt.
  • Taufiq Indra Rukmana, M.Farm., Apt.

 

Kelompok ini menekuni permasalahan yang berkaitan dengan pengujian dan pengembangan bahan serta sediaan Farmasi termasuk kosmetika dan makanan/minuman. Kegiatannya mencakup pengembangan dan modifikasi metode analisis maupun penerapannya terhadap berbagai bahan antara lain :

  • Pengujian mutu bahan baku obat maupun sediaan obat jadi
  • Pemantauan obat dan racun manusia dalam cairan tubuh manusia
  • Pengujian bahan tambahan dan cemaran sediaan kosmeti dan makanan/minuman.
  • Penelitian kimia bahan alam yang berpotensi dapat dimanfaatkan sebagai obat atau food suplement.
  • Ekstraksi dan isolasi senyawa aktif dari bahan alam atau hasil fermentasi bahan limbah industri (udang, kelapa sawit, dll)
  • Sintesis senyawa organik sebagai senyawa penuntun penemuan obat baru.
  • Elusidasi struktur senyawa aktif yang telah diisolasi.

Beberapa Publikasi :

  1. Yanuar, A., Dai, M., Meiyanto, E., Jenie, U.A., Supardjan, A.M. (2013). (2E,5E)-2,5-Bis(4-hydroxy-3-methoxy-benzylidene)cyclopentanone ethanol monosolvate. Acta Crystallographica Section E 2013.
  2. Harahap, Y., Prasaja, B., Lusthom, W., Hardiyanti, Azmi, F., Felicia, V., Yusvita,L.Y. (2013). Bioequivalence of trimetazidine modified release tablet formulations assessed in Indonesian subjects. Journal of Bioequivalence & Bioavailability, Vol : 5, No : 3, Hal : 117 – 120.
  3. Hayun, Leswara, N.D., Zarkasih, L. (2014). Penetapan Kadar Hidrokortison Asetat dalam Sediaan Krim mengandung Pengawet Nipagin secara Spektrofotometri Derivatif orde pertama. Pharmaceutical Sciences and Research Vol 1. No. 2, 2014.
  4. Nurjanah, M., Nurhidayah, U., Yanuar, A., Radji, M., Suryadi, H. (2013). Influence of Aeration and Metal Ions on Xylose Bioconversion from Water Hyacinth Hydrolysate into Xylitol by Debaryomyces hansenii. International Conference on Medicinal Chemistry and Timmerman Award 2013.
  5. Indrawan, I., Andarwulan, N., Yuliana, N.D., Yanuar, A. (2013). In Silico Study of Flavonoid Interacting with Dopamine D2 Receptor. International Conference on Medicinal Chemistry and Timmerman Award 2013.
  6. Suryadi, H., Yanuar, A., Harmita, Rachmadani, P.W., Mediana, R. (2013). Optimization Of Acid Hydrolysis Of Oil Palm Empty Fruit Bunch Using Oxalic Acid For Xylitol Production. International Conference on Medicinal Chemistry and Timmerman Award 2013
  7. Mutsnaini, L., Mediana, R., Suryadi, H., Harmita, Yanuar, A. (2013). Optimization of Xylitol Production with Various Substrate Concentration, Aeration, Metanol and Nitrogen Sources Addition Utilizing Oil Palm Empty Fruit Bunch Hydrolyzates by Debaryomyces hansenii UICC Y-276. International Conference on Medicinal Chemistry and Timmerman Award 2013.
  8. Hayun, Arrahman, A., Suryadi, H., Yanuar, A. (2013). Sonochemical Bromination of 2-Methyl-4(3H)-quinazolinone and 2-Methyl-6-nitro-4(3H)-quinazolinone using p-Toluensulfonic Acid – N-Bromosuccinimide (NBS). International Conference on Medicinal Chemistry and Timmerman Award 2013.
  9. Yanuar, A., Syahdi, R.R., Nugraha, B.H. (2013). Vina and AutoDock Parameter Optimization for HIV-1 Protease Virtual Screening Validation using Directory of Useful Decoys (DUD) Database. International Conference on Medicinal Chemistry and Timmerman Award 2013.
  10. Yanuar, A. (2014). Virtual Screening of Indonesian herbal database as HIV-1 protease inhibitor. Bioinformation, ISSN : 0973-2063, Vol : 10, Hal : 52.
  11. Yanuar, A., Hayun. (2014). Analisis Penambatan dan Simulasi Dinamika Molekuler Komplex Siklookgesinenase-2 dengan Beberapa Senyawa Turunan Kuinazolinon. Jurnal Farmasi Indonesia ISSN : 1412-1107, Vol : 7, No : 1, Hal : 50-59.
  12. Suhartanto, H., Li, X., Burrage, K., Yanuar, A. (2014). The Development Of Integrated Computing Platform To Improve User Satisfaction And Cost Efficiency Of In Silico Drug Discovery Activities. International Journal of Advancements in Computing Technology(IJACT),Volume 6, Number 2.
  13. Hayun, Arrahman, A., Suryadi, H., Yanuar, A. (2014). UjiAktivitasAntibakteri 1-[(Kuinazolin-4 on-2-IL) metil] p iridin-1-ium bromidadan 2- Bromo metilkuinazolin-4-on. Pharmaceutical Sciences and Research, Vol 3. No.1 2014.
  14. Hayun, Arrahman, A., Suryadi, H.,Yanuar, A. (2014). Microwave Assisted Synthesis of Pyridin-1-ium Salt of 6-Nitroquianzolin-4-one and Synthesis of its 6-Amino Analog under Ultrasonic Irradiation. ASIAN JOURNAL OF CHEMISTRY An International Peer Reviewed Research Journal of Chemistry, ISSN : 0970-7077, Vol : 26, NO. 19, Hal : 1-3.
  15. Harahap, Y., Andalusia, R., Crystalia, Y., Nurfaradilla, S.A., Harmita. (2014). Analysis of 06-Methylguanine in Cancer Patient Blood during Administration of Cyclophosphamide Using Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry. Journal of Advances in Medical and Pharmaceutical Sciences 2(1): 20-28.
  16. Yanuar, A. (2014). Molecular Dynamic Analysis of Docking Product of Complex a-Glucosidase with Sulochrin. MICAPS, Medan, Garuda Plaza Hotel Sulawesi Utara Indonesia. 03- 04 November 2014.
  17. Yanuar, A. (2014). Virtual screening of Indonesian herbal database (HerbalIDB) to HIV-1 Target Proteins. 3rd ICCST (International on Computation for Science and Technology, Bali, Indonesia, 23- 25 September 2014.
  18. Harahap, Y. (2014). DNA Adduct as Biomarker in Monitoring the Safety of Chemotherapy Usage in Cancer Patients. Seminar Nasional Fakultas Farmasi Universitas Andalas, Padang, Sumatera Barat Indonesia, 13-14 Juni 2014.
  19. Harahap, Y. (2014). Determination of O6-Methylguanine and N7-alkylguanine in Cancer Patients’ Blood during Administration of Cyclophosphamide by Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry. BIT 3rd Annual Conference and EXPO of AnalytiX-2014, Dalian, Liaoning China, 25-28 April 2014.
  20. Harahap, Y. (2014). Validated LC-MS/MS method for The Determination O6-Methylguanine in Cancer Patients’ Blood During Administration of Cyclophosphamide. 5th FIP Pharmaceutical Sciences World Congress 2014, Melbourne PSWC 2014, Melbourne Australia, 13-16 2014.
  21. Suhartanto, H., Yanuar, A., Bustamam, A. Basaruddin, T. (2015). Using Dedicated and Non Dedicated HPC Cluster and GPU NVIDIA Tesla C2070 Cloud computing envitonment to simulate Molecular Dynamics of PfENR Enzyme with AMBER. Intenational Journal of Advancements in Computing Technology (IJACT) Volume 7, Number 2.