Pharmacology and Toxicology Laboratory
Laboratory
Farmakologi dan Toksikologi
Kepala Laboratorium
Dr. apt. Heri Setiawan, M.Sc., CertDA.
Prof. Dr. apt. Anton Bahtiar, M.Biomed.
Prof. Dr. apt. Fadlina Chany Saputri, M.Si.
apt. Tri Wahyuni, M.Biomed., Ph.D.
apt. Meidi Utami Puteri, S.Farm., M.Sc., Ph.D.
apt. Nuriza Ulul Azmi, M.Sc.
Laboratorium ini melakukan kegiatan antara lain:
- Melakukan uji praklinik dan toksisitas obat-obat modern, obat tradisional, senyawa bahan alam dan zat kimia hasil sintesa lainnya.
- Uji farmakodinami dan farmakokinetik terhadap obat-obat kardiovaskuler, analgesik-antiinflamasi, antidiabetik oral, antihiperlipidemia, dan antihiperkolesterolemia.
- Penelitian toksisitas akut dan sub-kronis sediaan farmasi.
- Uji parameter farmakokinetika obat untuk menentukan bioavailabilitas/ ketersediaan hayati obat.
- Uji parameter biofarmasetik untuk menentukan absorpsi dan distribusi obat.
- Uji monitoring efek terapi penggunaan obat pada pasien.
Beberapa publikasi:
- Bahtiar, A. (2014). Effects of H (tBut)-L-Ser-Omethyl HCl on Breast Cancer Cells Line and Prostate Cells Line and its Effects on Bone Metastasis of Nude Mice. International Seminar on Tranlational Research in Cancer Chemoprevention, Indonesia Society for Cancer Chemoprevention,
Serpong Tangerang, Jawa Barat Indonesia. - Sari, S.P. (2014). Cost-Effectiveness Analysis of Ondansetron Generics and Brand Names on Breast Cancer Patients with Moderately Emetogenic Chemotherapy in National Cancer Center Dharmais Hospital Year 2012. ISPOR Indonesia Conference 2014, 23-24 Juni 2014.
- Bahtiar, A. (2014). Polar Fraction of Punica granatum L.peel extract increased osteoblast number on ovariectomized rat bone. International Journal of Herbal Medicine, Vol 2 (1): 65-70.
- Bahtiar, A. (2014). Functional Analysis of 70% Ethanolic of Akar Kelembak (Rheum Officinale Baill.) on 3T3 Preadipocyte Cell Lines in Osteogenic Medium. International Journal of Pharmacy and Pharmaceutical Sciences Vol 6 Issue 7.
- Saputri, F.C., Munim, A., Lukmanto, D., Aisyah, S.N., Rianndy, J.S. (2015). Inhibition of Angiotensin Converting Enzyme (ACE) Activity by Some Indonesia Edible Plants. IJPSR (International Journal of Pharmaceutical Sciences and Research), Vol. 6 (3) : 1054-1059, E-ISSN 0975-8232, P ISSN 2320-5148.